Immunological changes related to oral tolerance
نویسندگان
چکیده
منابع مشابه
Immunological changes related to oral tolerance
Background The default response to protein antigens in the intestine is the induction of systemic and local hyporesponsiveness (OT). There is increasing interest in the role of dietary manipulation and probiotics in the development and prevention of allergic and other diseases. Little is known how the environment and nutritional factors modulate systemic and local immune responses. This present...
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Grand ChallenGes The question of self–non-self discrimination, and thereby immunological tolerance, is as old as our appreciation of the receptor-diversity in the immune system. Initially negative selection of self-reactive lymphocytes by clonal deletion in primary lymphoid organs, enhanced by promiscuous expression of ectopic antigens in these organs, attracted attention. It became clear, howe...
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ژورنال
عنوان ژورنال: Clinical and Translational Allergy
سال: 2011
ISSN: 2045-7022
DOI: 10.1186/2045-7022-1-s1-s46